What is gemcitabine plus cisplatin?
Gemcitabine plus cisplatin (GC) is recommended as first-line treatment for advanced cholangiocarcinoma. We investigated the impact of GC in patients with unresectable hilar cholangiocarcinoma (HC) based on the time taken for effective biliary drainage (EBD).
Is gallbladder cancer a cholangiocarcinoma?
Gallbladder cancer is a rare cancer where malignant cancer cells form in the tissues of the gallbladder. Biliary tract cancer (also known as cholangiocarcinoma) is cancer that occurs in the bile ducts (tubes that transport bile from the liver).
Why is Gemzar given before cisplatin?
The recommendation to administer gemcitabine prior to cisplatin is based on results of phase 1 studies in adults with solid tumors, which indicated that this administration schedule may increase the generation of platinum-DNA adducts (potentially increasing efficacy) and reduce neutropenia.
How long can you stay on cisplatin?
Your course of chemotherapy You have chemotherapy as a course of several sessions (or cycles) of treatment over a few months. Each cycle of cisplatin usually takes 21 days (3 weeks).
Is gemcitabine and cisplatin an effective combination for Advanced gallbladder cancer?
Gemcitabine and Cisplatin is a highly effective combination chemotherapy in patients with advanced cancer of the gallbladder We evaluated the efficacy and toxicity of gemcitabine with or without cisplatin in 11 chemonaive patients with histologically confirmed advanced gallbladder cancer.
What is Gemzar and cisplatin used to treat?
Treatment Name: Gemcitabine (Gemzar®) + Cisplatin. Each of the medications in the gemcitabine and cisplatin (also known as gem/cis) regimen are designed to kill or slow growth of bladder cancer cells. Goals of therapy: Cisplatin plus gemcitabine is given to shrink bladder tumors and decrease symptoms from bladder cancer.
Can gemcitabine and cisplatin be taken together?
For example, combining gemcitabine and cisplatin may help people live longer than getting just gemcitabine alone. When chemo is given with radiation, most often 5-FU or capecitabine is used.
Can Gemzar be used to treat bladder cancer?
Treatment Name: Gemcitabine (Gemzar®) + Cisplatin. If metastatic disease is present (cancer has spread beyond the bladder to other areas of the body), cisplatin and gemcitabine are not commonly given with the goal of cure, but rather to shrink tumors, decrease symptoms from bladder cancer, and prolong life.
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