What is idiopathic retinal Periphlebitis?
INTRODUCTION. Eales disease is a form of retinal vasculitis typified by vascular inflammation in the peripheral retina. Because of its tendency to involve veins, the disorder has also been termed “periphlebitis retinae” and “idiopathic retinal periphlebitis.”
Is Eales disease curable?
Treatment of Eales Disease is symptomatic and supportive. The surgical process of coagulating tissue with a laser beam (laser panretinal photocoagulation) may be used to eliminate the deficiency of blood in the retina caused by constriction of blood vessels and to slow down excessive formation of blood vessel tissue.
Is Eales disease autoimmune?
Eales disease exact causes are not known. There have been some studies that implicate T-cells in the onset of the vasculitis, indicating that there may be an autoimmune factor to this disease.
What causes Eales disease?
The cause of Eales disease is unknown. Eales disease is a diagnosis of exclusion and is thought to be idiopathic. No causative drugs, environmental factors, or infectious agents for Eales disease have been identified.
Can retinal vasculitis be cured?
Treatment of retinal vasculitis typically involves high doses of cortisone-related medications, such as prednisone. Additionally, some diseases require immune suppression with medications, such as cyclosporine, chlorambucil, and cyclophosphamide.
How is retinal vasculitis treated?
Non-infectious retinal vasculitis is managed by systemic or local corticosteroids and steroid-sparing immunosuppressants. The local delivery of therapeutic agents can be done via intravitreal injections or periocular therapy, although the latter may not be sufficiently adequate for cases of severe retinal vasculitis.
Is retinal vasculitis serious?
Retinal vasculitis is a sight-threatening inflammatory eye condition that involves the retinal vessels. It may occur as an isolated idiopathic condition, as a complication of infective or neoplastic disorders, or in association with systemic inflammatory disease1 [Table 1].
How is eye vasculitis treated?