What is Interceed?

Interceed(TC7) is a fabric composed of oxidized, regenerated cellulose that was designed to reduce the formation of postsurgical adhesions. We evaluated Interceed(TC7) in a randomized, multicenter clinical study. Sixty-three infertility patients had bilateral pelvic sidewall adhesions removed at laparotomy.

What is seprafilm used for?

SEPRAFILM Adhesion Barrier is indicated for use in patients undergoing abdominal or pelvic laparotomy as an adjunct intended to reduce the incidence, extent and severity of postoperative adhesions between the abdominal wall and the under-lying viscera such as omentum, small bowel, bladder, and stomach, and between the …

What is Interceed in surgery?

Interceed (made by Johnson & Johnson) is a knitted fabric composed of a modified cellulose that swells and eventually gels after being placed on the injured site, and, like Seprafilm, forms a barrier and then is slowly absorbed over a period of days. It is approved for use in pelvic surgery.

Does seprafilm dissolve?

Seprafilm was evaluated in two forms, as a film and after it was well dissolved and compared to corresponding controls.

How do you prevent adhesions after surgery?

Prevention. Steps are taken during surgery to try and minimize the formation of adhesions. Some of these may include: shortening surgical time, keeping the tissues moist, gentle handling of any tissues or organs, and using starch –free and latex-free gloves.

Is surgicel an adhesion barrier?

In the Surgicel(®) group, there were 45.5% cases of adhesion formation; median score of adhesions was 6 (range, 4-10).

Is seprafilm an implant?

Seprafilm is a gel-like surgical implant made by Genzyme that has been on the market since 1996. It is an anti-adhesion device that prevents the formation of scar tissue between organs and tissues.

What is seprafilm adhesion barrier?

Seprafilm (chemically modified sodium hyaluronate/carboxymethylcellulose absorbable adhesion barrier) is a sterile, bioresorbable, temporary translucent adhesion barrier indicated for use in patients undergoing abdominal or pelvic laparotomy as an adjunct intended to reduce the incidence, extent and severity of …

What are adhesions?

An adhesion is a band of scar tissue that joins two surfaces of the body that are usually separate. The formation of scar tissue is the body’s repair mechanism in response to tissue disturbance caused by surgery, infection, injury (trauma) or radiation.

What does it feel like to have adhesions?

Most commonly, adhesions cause pain by pulling nerves within an organ tied down by an adhesion. Adhesions above the liver may cause pain with deep breathing. Intestinal adhesions may cause pain due to obstruction or pain from tugging during exercise or when stretching.

How do you use seprafilm?

Two procedures have been adopted for the application of Seprafilm in laparoscopic surgery. First, cut the film in pieces and roll together with a soft plastic holder. Then insert the roll into the abdomen via a 10–12 mm trocar, place the film pieces at the intended sites, and remove the soft plastic holder sheets.

What does adhesions look like?

Adhesions may appear as thin sheets of tissue similar to plastic wrap or as thick fibrous bands. The adhesion develops when the body’s repair mechanisms respond to any tissue disturbance, such as surgery, infection, trauma, or radiation, resulting in inflammation.

When did they stop using Seprafilm?

Marketed by Johnson & Johnson around 1904, it was still available in the early 1990s. In the United States, Interceed, Seprafilm and Adept are the three products approved by the U.S. Food and Drug Administration (FDA) for use as an adhesion barrier after abdominal or pelvic surgery.

What is Seprafilm made of?

Seprafilm is perhaps the most widely studied adhesion barrier, with more than 20 published studies that included over 4600 patients. Seprafilm is composed of chemically modified hyaluronic acid and carboxymethylcellulose. It is designed to separate planes of tissues after surgery for 3 to 7 days.

What is Interceed(TC7) fabric used for?

Is Interceed approved for use in surgery?

It is approved for use in certain types of pelvic or abdominal surgery. Interceed (made by Johnson & Johnson) is a knitted fabric composed of a modified cellulose that swells and eventually gels after being placed on the injured site, and, like Seprafilm, forms a barrier and then is slowly absorbed over a period of days.