What is Tc-99m DMSA?
Tc-99m DMSA. Tc-99m DMSA (dimercaptosuccinic acid) is a technetium radiopharmaceutical used in renal imaging to evaluate renal structure and morphology, particularly in pediatric imaging for detection of scarring and pyelonephritis. DMSA is an ideal agent for the assessment of renal cortex as it binds to the sulfhydryl groups in proximal tubules…
How do you administer technetium Tc99m succimer?
DOSAGE AND ADMINISTRATION. The suggested dose range for slow I.V. administration to be employed in the average patient (70 kg) for renal parenchymal imaging is 74-222 MBq, 2-6 mCi technetium Tc99m succimer injection. The product must be used between 10 minutes to 4 hours following preparation (see “Preparation” section).
Are the DMSA kit vials radioactive?
The contents of the kit vials are intended only for use in the preparation of DMSA Injection and are not to be directly administered to the patient. The contents of the kit vials are not radioactive. However, after Tc99m is added, adequate shielding of the final preparation must be maintained.
How long should DMSA be used for?
DMSA should be used between 10 minutes and 4 hours following reconstitution (see ” Preparation ” section). Any unused portion should be discarded after that time. Some patients with advanced renal failure may exhibit poor renal intake of Tc99m DMSA.