What is the function of homeobox genes?
Homeobox-containing genes encode DNA-binding proteins that regulate gene expression and control various aspects of morphogenesis and cell differentiation.
What is the role of Hox genes in development?
The role of the Hox genes is to specify positional identity in the embryo rather than the development of any specific structure. These positional values are interpreted differently in different embryos to influence how the cells in a region develop into, for example, segments and appendages.
What is the exact function of the HOXC8 gene?
HOXC8 serves as a transcription factor to regulate the expression of genes that are implicated in skeletal and neural development in embryogenesis and cancer progression.
What is the mutation for Antennapedia?
The mutation Antennapedia. Antennapedia (abbreviated Antp) is a HOM-C gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae.
What is antennapedia in biology?
Antennapedia. Antennapedia also refers to a gene complex in Drosophila which is responsible for formation and differentiation of the thoracic and head segments of the fly’s body.
What is Antp gene?
Antennapedia (abbreviated Antp) is a HOM-C gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs.
Is Antennapedia necessary for normal leg development in Drosophila?
Temporal and spatial regulation of the homeotic selector gene Antennapedia in the leg disc is necessary for normal leg development in Drosophila.