What is the mechanism responsible for gastroesophageal reflux?
The mechanisms involved in the pathogenesis of GERD are multiple and include: a) motor abnormalities, such as impaired lower oesophageal sphincter (LES) resting tone, transient LES relaxations (TLESR), impaired oesophageal acid clearance and delayed gastric emptying; b) anatomical factors, such as hiatal hernia; c) …
What is EsophyX procedure?
EsophyX TIF (Transoral Incision less Fundoplication) is a surgical procedure performed through the mouth which reconstructs the barrier between the stomach and esophagus to prevent stomach fluids from refluxing up into the esophagus.
Does stretta really work?
Stretta therapy has been studied the most in terms of treatments for GORD (Gastro Oesophageal Reflux Disease) and in over 40 clinical studies and 25,000 procedures it has proven to be a safe and effective treatment option. These studies also show that relief from the symptoms of reflux last from 4-10 years.
What affects LES GES pressure?
The physiologic factors controlling lower esophageal sphincter (LES) function are interrelated in a complex fashion and include the autonomic nerve supply, gastrointestinal hormones, and specific characteristics of the circular smooth muscle at the esophagogastric junction.
What mechanisms prevent gastric reflux when lying down?
To prevent this reflux, the lower esophageal sphincter (LES), a band of muscles at the lower end of the esophagus acts like a gate or valve. It permits food to pass down, and then closes to prevent gastric contents from coming back up (Figure One).
What is the purpose of fundoplication?
Fundoplication is a surgical procedure used to treat stomach acid reflux. During fundoplication, the top part of your stomach — called the fundus — is folded and sewn around the lower esophageal sphincter, a muscular valve at the bottom of your esophagus.
What is endoluminal fundoplication?
ENDOLUMINAL FUNDOPLICATION. This is a new procedure that can be done without making cuts. A special camera on a flexible tool (endoscope) is passed down through your mouth and into your esophagus. Using this tool, the doctor will put small clips in place at the point where the esophagus meets the stomach.
What is a EsophyX device?
EsophyX® Device The EsophyX device is designed to reconstruct the gastroesophageal valve (GEV) and help restore the GEV’s function as a reflux barrier. It is used to perform the TIF® procedure — Transoral Incisionless Fundoplication — by enabling the creation of a 2-3 cm, 270° esophagogastric fundoplication.
Who can get Stretta procedure?
Potential candidates for Stretta would be those with GERD who have breakthrough symptoms, such as, persistent heartburn and/or regurgitation despite escalating doses of PPI (refractory GERD), patients with GERD who are symptomatic because they cannot tolerate PPIs (2% of PPI users), those who desire to stop drug …
What is LES function?
The lower esophageal sphincter (LES) is a bundle of muscles at the low end of the esophagus, where it meets the stomach. When the LES is closed, it prevents acid and stomach contents from traveling backwards from the stomach.
What is the function of gastroesophageal sphincter?
Sphincters at the upper esophagus and gastroesophageal junction reduce reflux and regurgitation. The lower esophageal sphincter located at the gastroesophageal junction acts to curtail reflux of gastric contents into the esophagus because the acidic gastric secretion is injurious to the esophageal mucosa.