What is the therapeutic level of theophylline?
Therapeutic serum levels of theophylline are between 10 to 20 mcg/ml. Most adults achieve these concentrations with daily slow-release oral theophylline preparations, 200-400 mg (approximately 10 mg/Kg) twice a day.
When do you measure Aophylline levels?
Monitoring requirements Plasma-theophylline concentration is measured 5 days after starting oral treatment and at least 3 days after any dose adjustment. A blood sample should usually be taken 4–6 hours after an oral dose of a modified-release preparation (sampling times may vary—consult local guidelines).
What is theophylline lab test for?
This test measures the level of theophylline in your blood. Theophylline is a chemical similar to caffeine. It’s sometimes used as a medicine to treat lung conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiolitis.
What ingredients are in theophylline?
Each extended-release tablet for oral administration contains either 300 mg or 450 mg of Theophylline anhydrous, USP. Tablets also contain as inactive ingredients: anhydrous lactose, hypromellose, lactose monohydrate, magnesium stearate and povidone.
What is the therapeutic level of phenobarbital?
The therapeutic range for adults taking phenobarbital is 15-40 micrograms/milliliter (mcg/ml) (65-173 micromole/liter) for seizure treatment, and 5-15 micrograms/milliliter (mcg/ml) (22-65 micromole/liter) for sedative-hypnotic use.
What elevated theophylline levels?
Administration of allopurinol, oral contraceptives, cimetidine, erythromycin, quinolone antibiotics, fluvoxamine, zileuton, and zafirlukast has been shown to increase theophylline levels.
How do you measure Aophylline levels?
Answer: If the sustained release theophylline is given twice a day, then a good time to measure a level is 4 hours after the morning dose. If the sustained release theophylline is given only once a day, then the blood should be drawn 8-12 hours after the dose.
Is Aminophylline the same as theophylline?
Aminophylline is the ethylenediamine salt of theophylline. Theophylline stimulates the CNS, skeletal muscles, and cardiac muscle. It relaxes certain smooth muscles in the bronchi, produces diuresis, and causes an increase in gastric secretion. Aminophylline is the ethylenediamine salt of theophylline.