What is the treatment for plasma cell dyscrasia?
The use of serotherapy to treat patients with plasma cell dyscrasias (PCDs) has been sought by us and others. Candidate antigens that have been targeted or proposed for targeting in PCDs include the immunoglobulin idiotype, CD19, CD38, CD54, CD126, HM1. 24, and Muc-1 core protein.
Is plasma cell dyscrasia curable?
Multiple myeloma (MM) is an incurable plasma cell dyscrasia and the second most frequent hematologic malignancy, with an incidence of 5.85/100,000 adults in Western countries and a 5-year survival rate of 48.5% [1].
Is pneumonia common with multiple myeloma?
Two in three infection-related deaths in myeloma patients are caused by pneumonia. The Centers for Disease Control and Prevention (CDC) and the National Comprehensive Cancer Network (NCCN) recommend vaccinating myeloma patients with a pneumococcal vaccine.
What is the treatment for Plasmacytoma?
Treatment of extramedullary plasmacytoma may include the following: Radiation therapy to the tumor and nearby lymph nodes. Surgery, usually followed by radiation therapy. Watchful waiting after initial treatment, followed by radiation therapy, surgery, or chemotherapy if the tumor grows or causes signs or symptoms.
What does plasma cell dyscrasia mean?
Definition. Plasma cell dyscrasias are a monoclonal proliferation of plasma cells that produce a clonal immunoglobulin protein (i.e., monoclonal gammopathies or paraproteinemias). They are derived from malignant B lymphocytes. Common plasma cell dyscrasias include multiple myeloma and Waldenström’s macroglobulinemia.
What blood dyscrasias means?
Definition of blood dyscrasia : an abnormal condition or disease of the blood.
What is plasma cell dyscrasia mean?
What is the meaning of blood dyscrasias?
How does multiple myeloma affect the lungs?
The intraparenchymal causes of respiratory failure from multiple myeloma include alveolar septal amyloidosis, plasma cell infiltration of lung parenchyma, accumulation of alveolar paraproteins, and metastatic calcification of the alveolar walls and blood vessels.
What kind of infections do you get with multiple myeloma?
The most common infections were meningitis, septicemia, pneumonia, osteomyelitis, cellulitis, and pyelonephritis. The risk of viral infections was 10-fold higher overall and 18-fold during the first year. Influenza infection and herpes zoster were the most frequent viral infections.