What is the ULN for ALT?
The ULN (95th percentile) of ALT is 34 U/L for males and 24 U/L for females and the ULN of AST is 32 U/L for males and 26 U/L for females. Serum ALT was strongly associated with BMI and AST was strongly associated with gender.
What should the ratio of AST to ALT be?
A normal AST:ALT ratio should be <1. In patients with alcoholic liver disease, the AST:ALT ratio is >1 in 92% of patients, and >2 in 70%. AST:ALT scores >2 are, therefore, strongly suggestive of alcoholic liver disease and scores <1 more suggestive of NAFLD/NASH.
What is a high AST ALT ratio?
An elevated serum AST in relation to serum ALT (alanine aminotransferase) has been proposed as an indicator that alcohol has induced organ damage. Thus, when AST/ALT ratio is >1.5, this is considered as highly suggestive that alcohol is the cause of the patient’s liver injury (Correia et al., 1981; Salaspuro, 1987).
What does slightly elevated AST and ALT mean?
ALT stands for alanine aminotransferase, which is another type of liver enzyme. If you have high levels of AST and/or ALT, it may mean that you have some type of liver damage. You may also have an AST test part of a series of liver function tests.
What is ULN of AST?
Results: “ULN of ALT” was 34 U/L in men and 24 U/L in women and “ULN of AST” was 32 U/L in men and 26 U/L in women in the blood donor database.
What is ULN in liver function test?
it is common practice to describe abnormal LFTs by their relationship to the upper limit of normal (ULN) for that test, or by ratios of the values of the tests, to control for variations in normal ranges between labs and techniques of analysis.
Should ALT be higher than AST?
In addition, patients with Wilson’s disease or cirrhosis due to viral hepatitis may have an AST that is greater than the ALT, though the ratio typically is not greater than two. When the AST is higher than ALT, a muscle source of these enzymes should be considered….
| AST/ALT ratio | |
|---|---|
| LOINC | 16325-3, 1916-6 |
What is ULN?
The Unique Learner Number (ULN) is a 10-digit reference number which is used alongside and to access the Personal Learning Record of anyone over the age of 13 involved in UK education or training. The ULN can also help learners throughout their lifelong learning, particularly when accessing careers advice.