Why do vasodilators cause tachycardia?
While vasodilators are successful in controlling hypertension, these medications possess a myriad of side effects. Reflex tachycardia is the primary adverse effect of these drugs, as a consequence of the medication induced baroreflex response compensating for the sudden medication decrease in vascular resistance.
Does hydralazine cause bradycardia?
It is generally recognized that the vasodilator hydralazine produces hypotension accompanied by baroreflex-mediated tachycardia. In some experimental conditions, however, the accompanying heart rate change is bradycardia, a paradoxical response which has not been satisfactorily explained.
What are the symptoms of hydralazine?
Hydralazine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- flushing.
- headache.
- upset stomach.
- vomiting.
- loss of appetite.
- diarrhea.
- constipation.
- eye tearing.
What is reflex tachycardia?
If blood pressure decreases, the heart beats faster in an attempt to raise it. This is called reflex tachycardia. This can happen in response to a decrease in blood volume (through dehydration or bleeding), or an unexpected change in blood flow.
Does tachycardia increase cardiac output?
Tachycardia. Tachycardia of atrial or ventricular origin reduces stroke volume and cardiac output particularly when the ventricular rate is greater than 160 beats/min. The stroke volume becomes reduced because of decreased ventricular filling time and decreased ventricular filling (preload) at high rates of contraction …
What are the most common side effects of hydralazine?
Headache, pounding/fast heartbeat, loss of appetite, nausea, vomiting, diarrhea, or dizziness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Why does hydralazine cause tachycardia?
Hydralazine. The decrease in BP provokes a profound reflexive increase in sympathetic activity, causing reflex tachycardia and increased cardiac output, myocardial work, and myocardial oxygen demand. The increase in sympathetic activity also causes significant sodium and fluid retention, resulting in volume expansion.
What are the side effects of hydralazine?
chest pain,fast heart rate;
Is hydralazine a good blood pressure medicine?
Hydralazine is used to control high blood pressure. Treatment with hydralazine is usually long-term. Although many people with high blood pressure (hypertension) do not feel unwell, it is still important that high blood pressure be treated.
When to take hydralazine medication?
Generally, hydralazine is taken four times a day. However, if taking this medication three times a day, then roughly every eight hours a dose should be taken. Therefore, it should be taken once in the morning, afternoon and evening. The times can fluctuate based on when the individual took their first dose.