What is Monckeberg medial calcific sclerosis?

What is Monckeberg medial calcific sclerosis?

Monckeberg medial calcific sclerosis (MCS) is a ring-like calcification of the vascular media of small to medium sized vessels without associated intimal thickening. Almost exclusively, MCS is the underlying condition in what is referred to as breast arterial calcification (BAC) detected at mammography.

What causes medial calcification?

Medial calcifications, for example, are most often associated with kidney disease, diabetes, hypertension, and advanced age. Intimal calcifications are associated with blocked arteries and blood clots.

What is medial arterial calcification?

Medial arterial calcification (MAC), also known as Mönckeberg arteriosclerosis, is a condition that leads to stiffening of the elastic layer of the arterial wall, but in contrast to intimal calcification, it does not obstruct the arterial lumen (2).

What causes Monckeberg sclerosis?

Mönckeberg’s arteriosclerosis, also called medial calcific sclerosis or Mönckeberg’s sclerosis, is a form of vessel hardening due to increased calcium deposits in the tunica media layer.

What is Monckeberg?

Monckeberg’s sclerosis is a rare and low prevalence disease of unknown cause in which small and medium size arteries suffer calcification of the middle layer, leading to a reduction in caliber. Clinically, the disease manifests by the appearance of arterial type ulcers on the skin of upper and lower extremities.

What is erythro sclerosis?

Arteriosclerosis is the thickening, hardening, and loss of elasticity of the walls of arteries.

Who is Monckeberg?

Monckeberg’s sclerosis is a disease of unknown aetiology characterised by calcification of the media of small-sized and medium-sized arteries1 first described by Johann Georg Monckeberg in 19032 for whom it is eponymously named. The result is progressive stiffening of the elastic layer of the arterial wall.