What does urine immunofixation mean?
Urine immunofixation is a test that looks for abnormal proteins in urine. In particular, it looks for an abnormal protein known as M-protein. An M-protein is a kind of abnormal immunoglobulin created by plasma cells, which are a type of white blood cells.
What does a positive immunofixation mean?
Positive results from the test indicate the presence of abnormal Ig. This may suggest the existence of an underlying health condition, such as: an immune system disorder. multiple myeloma.
Does multiple myeloma cause protein in urine?
About 50% to 80% of people with multiple myeloma have Bence-Jones proteins in their urine. If you have been diagnosed with multiple myeloma, a Bence-Jones protein urine level can also be used as one of several ways to find out the stage of the cancer. Stage of cancer means how much it has grown and spread.
What does abnormal immunofixation mean?
An abnormal result may be due to: Amyloidosis (buildup of abnormal proteins in tissues and organs) Leukemia or Waldenström macroglobulinemia (types of white blood cell cancers) Lymphoma (cancer of the lymph tissue) Monoclonal gammopathy of unknown significance (MGUS)
Does multiple myeloma affect the bladder?
Extramedullary manifestation is most frequently in lymphatic tissue, followed by the liver, kidneys, skin, and central nervous system (CNS). ‘ Urinary bladder invasion is exceedingly rare; only two postmortem cases have been rep~rted.
Does multiple myeloma cause foamy urine?
Multiple myeloma, specifically – a type of cancer that forms in the plasma cells of your blood – can lead to extra protein in the urine (and cause it to look foamy).
What does Immunofixation electrophoresis test for?
An immunofixation blood test, also known as protein electrophoresis, measures certain proteins in the blood. Proteins play many important roles, including providing energy for the body, rebuilding muscles, and supporting the immune system. There are two main types of proteins in the blood: albumin and globulin.