How is levothyroxine administered?
Levothyroxine comes as a tablet and a capsule to take by mouth. It usually is taken once a day on an empty stomach, 30 minutes to 1 hour before breakfast. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Can levothyroxine be given IM?
Conclusions: Available data suggest that intramuscular administration of levothyroxine is effective, generally safe, and could be a viable alternative to oral levothyroxine in non-compliant patients or those with GI malabsorption.
What is the best way to take levothyroxine?
Typically, patients are advised to take their levothyroxine first thing in the morning, at least 30 minutes but preferably an hour before eating, on an empty stomach and with only water. The goal is to achieve consistency in taking the medication to avoid fluctuations in thyroid levels and variable control of symptoms.
Can levothyroxine be IV?
The recommended loading dose of Levothyroxine Sodium Injection is 300 mcg to 500 mcg administered intravenously. The recommended maintenance dose of Levothyroxine Sodium Injection is 50 mcg to 100 mcg administered intravenously daily until the patient can tolerate oral therapy.
When do you give IV levothyroxine?
An initial intravenous loading dose of Levothyroxine Sodium for Injection between 300 to 500 mcg, followed by once daily intravenous maintenance doses between 50 and 100 mcg, should be administered, as clinically indicated, until the patient can tolerate oral therapy.
Can levothyroxine be injected?
Levothyroxine injection is used to treat myxedema coma (severe hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. The powder form of levothyroxine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed.
Can Synthroid be given IV push?
INDICATIONS AND USAGE Levothyroxine Sodium for Injection can be used intravenously (IV) whenever a rapid onset of effect is critical, and either IV or intramuscularly (IM) in hypothyroid patients whenever the oral route is precluded for long periods of time.
How does levothyroxine adjust to TSH?
If the TSH is not at the desired goal, the levothyroxine dose can be adjusted up or down. TSH values that are slightly out of range may be corrected by a single dose increment or decrement, such as increasing from 100 to 112 μg or decreasing from 175 to 150 μg.
Can you take levothyroxine and amlodipine together?
No interactions were found between amlodipine and levothyroxine. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
How do you administer levothyroxine IV?
After reconstitution as directed, do not add levothyroxine sodium for injection to other IV fluids or medications. Inject IV via Y-site or a 3-way stopcock at a rate not to exceed 100 mcg per minute. In younger patients, inject over 2 to 3 minutes.
What should you assess before giving levothyroxine?
Examination and Evaluation Assess heart rate, ECG, and heart sounds, especially during exercise (See Appendices G, H). Report any rhythm disturbances or symptoms of increased arrhythmias, including palpitations, chest discomfort, shortness of breath, fainting, and fatigue/weakness.
When should levothyroxine be administered?
How and when to take levothyroxine. Take levothyroxine once a day in the morning, ideally at least 30 minutes before having breakfast or a drink containing caffeine, like tea or coffee. Food and caffeinated drinks can both stop your body taking in levothyroxine properly so it does not work as well.