What are contraindications of Tocolytics?
Contraindications to tocolytics Pregnant woman has severe pregnancy-induced hypertension, severe eclampsia/preeclampsia, active vaginal bleeding, placental abruption, a cardiac disease, or another condition which indicates that the pregnancy should not continue.
What are two 2 contraindications for the administration of terbutaline during labor?
Beta-mimetics (eg, terbutaline) may be contraindicated in the presence of cardiac arrhythmia, valvular disease, and ischemic heart disease and may alter glucose homeostasis in patients with diabetes.
What are the conditions or criteria before Tocolytic therapy is considered?
Criteria that indicate consideration of tocolytic therapy include more than 6 contractions per hour resulting in a demonstrated cervical change or presumed prior cervical change (transvaginal cervical length < 2.5 cm, >50% cervical effacement, or cervical dilation ≥2 cm).
Why are Tocolytics contraindicated in Pprom?
Prophylactic tocolysis begun before the onset of labor increases the likelihood of delaying the onset of labor for 1-2 days, but not beyond. Aggressive long-term tocolysis may increase the maternal risk of chorioamnionitis and endometritis.
What is the contraindication of oxytocin?
The induction or continuance of labor with oxytocin should be avoided when the following conditions or situations are present: evidence of fetal distress, fetal prematurity, abnormal fetal position (including unengaged head), placenta previa, uterine prolapse, vasa previa, cephalopelvic disproportion, cervical cancer.
What are contraindications for terbutaline?
Who should not take TERBUTALINE SULFATE?
- overactive thyroid gland.
- diabetes.
- a metabolic condition where the body cannot adequately use sugars called ketoacidosis.
- low amount of potassium in the blood.
- high blood pressure.
- diminished blood flow through arteries of the heart.
- a low supply of oxygen rich blood to the heart.
Why is terbutaline contraindicated in diabetes?
Glucose levels returned to preintervention values with the cessation of terbutaline therapy. Conclusions: It has been previously suggested that terbutaline increases hepatic glycogenolysis, which may aggravate glucose intolerance.
Who is a candidate for tocolytic therapy?
Patients at <34 0/7 weeks with demonstrated cervical change are candidates for tocolysis.
When is indomethacin contraindicated for Tocolysis?
Women who are more than 32 weeks pregnant should avoid taking indomethacin, given the potential for heart problems in the baby. Women with a history of ulcers, bleeding disorders, or kidney or liver disease should also avoid taking indomethacin.
Can you give Tocolytics in Pprom?
In women with preterm premature rupture of membranes (PPROM), the use of tocolysis is still controversial. In theory, tocolysis may prolong pregnancy in women with PPROM, thereby allowing for the corticosteroid benefit and reducing the morbidity and mortality associated with prematurity.
When do you use Tocolytics in Pprom?
Tocolytic treatments are widely administered after very preterm PROM15,16,17,18. They aim at prolonging gestation to allow for gains in fetal maturity as well as administration of antenatal steroids and in utero transfer.
What are the obstetric contraindications of tocolytic treatments?
Usual obstetrical contraindications of tocolytic treatments (infection, genital haemorrhage, fetal distress and certain maternal conditions) are often determined on a case by case basis, rather than upon evidence based medicine.
When are specific tocolytic agents contraindicated in the treatment of allergies?
Specific tocolytic agents should not be used whenever known allergies exist. Indomethacin is contraindicated in the presence of aspirin-induced asthma, coagulopathy, or significant liver disease.
What are the side effects of tocolytics?
Here are some of the side effects of tocolytics, broken down by drug class: Major side effects: Cardiac arrhythmias (tachycardia), hypotension, hyperglycemia, pulmonary edema
Do tocolytic medications improve perinatal or neonatal outcomes?
There is no proof however for their beneficial effect on perinatal or neonatal outcomes. Usual obstetrical contraindications of tocolytic treatments (infection, genital haemorrhage, fetal distress and certain maternal conditions) are often determined on a case by case basis, rather than upon evidence based medicine.
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