What are the indications for splenectomy?

What are the indications for splenectomy?

Indications for splenectomy include hypersplenism, incidental to other abdominal procedures, trauma, Hodgkin’s staging, and other splenic disease. Hodgkin’s staging has become the most frequent indication for splenectomy during the past five years, whereas splenectomy for hypersplenism has decreased.

What is an emergency splenectomy?

An emergency splenectomy involves placement in the supine position, exposure of the peritoneal cavity and achievement of temporary hemostasis. The spleen should be mobilized from its ligamentous attachments, with ligation of the splenic pedicle, achievement of hemostasis, complete resection, and abdominal closure.

Why does splenectomy increased risk of infection?

The factors responsible for an increased incidence of infection and propensity for severity following a splenectomy include insufficient opsonizing filter function of the spleen, delayed and impaired production of immunoglobulin (Ig), lack of splenic macrophages, and minimal tufts production [5].

What happens if your spleen ruptures?

A ruptured spleen (a fist-sized organ located in the left upper abdomen) occurs when the surface of this organ is injured, which can lead to internal bleeding. Symptoms include pain in the abdomen and nausea. A ruptured spleen is treated with surgery if the patient has lost a large amount of blood.

What happens when your spleen ruptures?

Why does thrombocytosis occur after splenectomy?

The early, highly significant thrombocytosis, following both splenectomy and general surgery, is caused by increased production of platelets due to the surgical trauma. This is caused by a direct action on bone marrow MK by transforming 2N-8N MK into higher ploidy classes.

What is post-splenectomy infection?

An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen.