What does cortical laminar necrosis mean?
Cortical laminar necrosis (CLN) is radiologically defined as high intensity cortical lesions on T1 weighted MRI images following a gyral distribution. Histopathologically, CLN is characterised by pannecrosis of the cortex involving neurones, glial cells, and blood vessels.
What causes laminar necrosis?
The causes of laminar necrosis included the following: infarction in 4 patients, Moyamoya disease in 2, hypoxic-ischemic injury in 2, meningoencephalitis in 2, shaken baby syndrome in 1, encephalopathy from severe infection in 1, status epilepticus in 1, citrullinemia in 1, and cerebral injury from posterior reversible …
Does laminar necrosis enhance?
Contrast enhancement of the laminar lesions was prominent at 1-2 months and became less apparent from 3 months, but could be seen up to 8 months.
What is cerebral cortex?
The cerebral cortex is a sheet of neural tissue that is outermost to the cerebrum of the mammalian brain. It has up to six layers of nerve cells. The cortex is gray because nerves in this area lack the insulation (myelin) that makes most other parts of the brain appear to be white.
What causes cerebral cortical necrosis?
Cortical Laminar Necrosis: Causes This can occur because of an obstruction such as a blood clot or plaque build-up that prevents blood flow. Strokes can also be the result of an aneurysm which occurs when the blood vessels to the brain burst, which prevents the blood from reaching parts of the brain.
What is a cortical structure?
Most of the cortex that covers the cerebral hemispheres is neocortex, defined as cortex that has six cellular layers, or laminae. Each layer comprises more or less distinctive populations of cells based on their different densities, sizes, shapes, inputs, and outputs.
What is cortical enhancement?
Gyral enhancement, also known as gyriform, cortical, or grey matter enhancement, is a pattern of contrast enhancement in the superficial brain parenchyma that conforms to the serpentine morphology of the cerebral gyri.
What happens if the cerebral cortex is damaged?
The cerebral cortex plays a crucial role in nearly all brain functions. Damage to it can cause many cognitive, sensory, and emotional difficulties.
What is luxury perfusion?
Luxury hyper-perfusion is defined by the state of excessive brain blood flow in demand of the metabolic rate and oxygen demand of the brain tissue. It is nonnutritive flow to the infarcted tissue because of abnormal autoregulation system [4].