What does CTSS mean?

What does CTSS mean?

CTSS (Cathepsin S) is a Protein Coding gene. Diseases associated with CTSS include Cercarial Dermatitis and Mandibular Cancer.

What is cathepsin B (CTSB)?

Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Sep 2020] CTSB (Cathepsin B) is a Protein Coding gene.

Is there an active enhancer element for CTSB in tandem duplications?

{ECO:0000269 PubMed:28457472}. Note=The gene represented in this entry is involved in disease pathogenesis. Tandem duplications in a non-coding genomic region containing an active enhancer element for CTSB result in CTSB abnormal expression with pathological consequences.

What is the pathophysiology of CTSB disease?

Diseases associated with CTSB include Keratolytic Winter Erythema and Annular Erythema . Among its related pathways are A-beta Plaque Formation and APP Metabolism and Activated TLR4 signalling . Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity .