What does Granulocytopenia mean?
Granulocytopenia is defined as a decrease of peripheral blood granulocytes below lower limit of normal range. Patients with severe granulocytopenia – agranulocytosis exhibit < 0.5 × 109/l granulocytes in peipheral blood.
What is a granulocyte?
Listen to pronunciation. (GRAN-yoo-loh-SITE) A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. Neutrophils, eosinophils, and basophils are granulocytes.
What is acquired agranulocytosis?
Acquired agranulocytosis is a rare, drug-induced blood disorder that is characterized by a severe reduction in the number of white blood cells (granulocytes) in the circulating blood. The name granulocyte refers to grain-like bodies within the cell. Granulocytes include basophils, eosinophils, and neutrophils.
What is pancytopenia?
A condition in which there is a lower-than-normal number of red and white blood cells and platelets in the blood. Pancytopenia occurs when there is a problem with the blood-forming stem cells in the bone marrow.
Which antipsychotic causes granulocytopenia?
Clozapine is a well-known drug that is used in treatment-resistant schizophrenia, but granulocytopenia, which may lead to a potentially fatal condition such as agranulocytosis, limit its use.
What medication increases neutrophils?
Neupogen can be very effective for increasing the level of neutrophils in your body to reduce your risk of infection. Many people experience some bone pain and a fever, but this is usually very mild. Fortunately, the medication is needed only as long as you are receiving chemotherapy and can then be discontinued.
What is GRA in blood work?
Glucocorticoid-remediable aldosteronism (GRA): diagnosis, variability of phenotype and regulation of potassium homeostasis.
What is an example of an Agranulocyte?
agranulocyte Any white blood cell (see leucocyte) with a nongranular cytoplasm and a large spherical nucleus; lymphocytes and monocytes are examples. Agranulocytes are produced either in the lymphatic system or in the bone marrow and account for 30% of all leucocytes.
Is Granulocytopenia the same as neutropenia?
Also known as granulocytopenia, agranulocytosis is a severe form of neutropenia. Neutropenia is lower-than-normal levels of white blood cells.
What is a polycythemia?
Polycythemia vera is a rare blood disorder in which there is an increase in all blood cells, particularly red blood cells. The increase in blood cells makes your blood thicker. This can lead to strokes or tissue and organ damage.