What is an extremely high alkaline phosphatase?
Values above 130 U/L are usually considered to be high. High levels of ALP in the blood may indicate bone, liver, or bile duct disease. ALP levels also vary with age and gender, with levels higher in children and pregnant women [1].
Is 400 high for alkaline phosphatase?
Diagnosis. Serum alkaline phosphatase level <90 U/L. The normal range is 80–350 U/L, however, growing children often have levels well in excess of these values (>400 U/L).
What are the causes of elevated alkaline phosphatase?
| Marked elevation (≥4 times the upper limit of normal)* | Extrahepatic biliary obstruction¶ |
|---|---|
| Moderate elevation (<4 times upper limit normal) | High bone turnover Growth Healing fractures Osteomalacia Paget disease of bone Osteogenic sarcoma, bone metastasis Hyperparathyroidism Hyperthyroidism |
What is alkaline phosphatase (ALP)?
Alkaline Phosphatase. What is an Alkaline Phosphatase Test? An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. ALP is an enzyme found throughout the body, but it is mostly found in the liver, bones, kidneys, and digestive system.
What should I do if my alkaline phosphatase is high?
If your ALP level is high, your doctor may have you take another test, called an ALP isoenzyme test, to determine whether the alkaline phosphatase in your blood is coming from your liver or your bones.
Does alkaline phosphatase level increase during pregnancy?
It is said that the alkaline phosphatase level increases during pregnancy. It is 68.2U/I and 75.9 U/I during the first trimesters. I rise to 126.7 to 178.8 and 234 U/I during the seventh, eighth, and ninth months respectively. This increase is due to more alkaline phosphatase production by the placenta during pregnancy.
Is vitamin D deficiency associated with high alkaline phosphatase?
Vitamin D deficiency is usually accompanied by elevated levels of total alkaline phosphatase in the blood. However, it is not the best indicator of vitamin D deficiency [ 24 ]. Alzheimer’s disease, Paget’s disease, and vitamin D deficiency may all underlie high alkaline phosphatase levels.