What is CUROSURF used for?

What is CUROSURF used for?

Curosurf is used to treat or prevent Respiratory Distress Syndrome (RDS) in newborn babies. Most babies are born with a substance in their lungs known as ‘surfactant’. This substance lines the lungs and stops them from sticking together and so makes normal breathing possible.

When do you administer CUROSURF?

The initial recommended dose of CUROSURF is 2.5 mL/kg birth weight. Up to 2 repeat doses of 1.25 mL/kg birth weight each may be administered at approximately 12‑hour intervals. A total of 4 doses of Survanta (4 mL/kg birth weight) can be administered no more frequently than every 6 hours in the first 48 hours of life.

When do you give surfactant?

Ideally the dose should be given within 1 hr of birth but definitely before 2 hours of age. A repeat dose should be given within 4 – 12 hours if the patient is still intubated and requiring more than 30 to 40% oxygen.

What is the classification of CUROSURF?

Curosurf is a prescription medicine used to treat the symptoms of Respiratory Distress Syndrome (RDS) in premature infants. Curosurf may be used alone or with other medications. Curosurf belongs to a class of drugs called Lung Surfactants.

How long is CUROSURF good for?

Pull the plastic cap with the aluminum portion downwards. Remove the whole ring by pulling off the aluminum wrapper. Remove the rubber cap to extract content. Unopened, unused vials of CUROSURF suspension that have warmed to room temperature can be returned to refrigerated storage within 24 hours for future use.

How do you administer survanta?


  1. Slowly withdraw the entire contents of the vial into a plastic syringe through a large-gauge needle (e.g., at least 20 gauge).
  2. Attach the premeasured 5 French end-hole catheter to the syringe.
  3. When administering SURVANTA using a 5 French end-hole catheter, administer in four quarter-dose aliquots.

How is surfactant given?

Methods to deliver surfactant The surfactant is administered via a thin catheter into the trachea in small aliquots, while the baby is spontaneously breathing on CPAP support. In infants 29-32 weeks gestation, LISA may reduce the occurrence of pneumothorax and need for mechanical ventilation.

Is CUROSURF synthetic?

Animal-derived surfactants that contain surfactant proteins (Survanta, Infasurf, and Curosurf) perform clinically better than Exosurf, a synthetic surfactant containing only phospholipids, primarily in outcomes related to acute management of respiratory distress syndrome (RDS; faster weaning and pneumothorax) but not …

When was curosurf invented?

In the 1980s Bengt Robertson and Tore Curstedt developed a porcine surfactant, Curosurf (named after their surnames), which was effective in immature animals and was used in a pilot clinical trial beginning in 1983.

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