What is exenatide used for?
Exenatide is an injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Bydureon is a long-acting form of exenatide. Bydureon is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
What is the name of the lizard that contains exenatide in its saliva?
Exenatide is a synthetic form of a hormone called exendin-4 that occurs naturally in the saliva of the Gila monster, a large venomous lizard native to the southwestern United States and northwestern Mexico.
What is Gila monster venom used for?
A synthetic version of the hormone was developed for use in a drug to treat type 2 diabetes. In addition to regulating blood sugar, exendin-4 may also reduce appetite and help control obesity. In the wild, venom may help Gila monsters immobilize prey or defend themselves when a predator or human disturbs them.
Which medication was derived from the saliva of the Gila monster?
The discovery of the hormone exendin-4 in Gila monster saliva led to the development of a new drug called exenatide, which has the ability to help those with type 2 diabetes.
What is the difference between liraglutide and exenatide?
In conclusion, liraglutide 1.2mg once daily appears to decrease HbA1c and fasting plasma glucose significantly better than exenatide 10µg twice daily, with no difference in adverse events. Liraglutide has the added benefit of once-daily injection compared to twice daily with exenatide.
Is exenatide insulin?
Byetta (generic name Exenatide) is used to treat people with type 2 diabetes Byetta is an injectable drug that helps to lower blood sugar levels in a way that does not promote weight gain. Whilst Byetta is injected, it is not insulin, but is a drug in the class of diabetic drugs called incretin mimetics.
How bad is Gila monster venom?
The bite of a Gila monster is very strong, and the lizard may not loosen its grip for several seconds. It may even chew so that the venom goes deeper into the wound. A Gila monster bite is painful to humans, but it rarely causes death.
Is Gila monster venom fatal?
Venom. The Gila monster is one of only a handful of venomous lizards in the world. Its venom is a fairly mild neurotoxin. And though a Gila bite is extremely painful, none has resulted in a reported human death.
What is the most venomous lizard in the world?
Gila monster Heloderma suspectum
Based upon current research results, the world’s most venomous lizard is the Gila monster Heloderma suspectum, native to the southwestern USA and northwestern Mexico. LD50 (lethal dose) values for its venom as low as 0.4 mg/kg have been recorded when administered intravenously in mice.
What is bydureon made from?
The main ingredient in both Bydureon and Byetta is exenatide, a hormone derived from the saliva of the Gila monster, a poisonous lizard found in the Southwestern United States and Mexico.
Is dulaglutide the same as liraglutide?
Trulicity contains the active drug dulaglutide. Victoza contains the active drug liraglutide. Dulaglutide and liraglutide belong to the same drug class: glucagon-like peptide-1 agonists. (A drug class is a group of medications that work in a similar way.)
What is the difference between dulaglutide and liraglutide?
Dulaglutide has higher treatment persistence and less treatment discontinuation than liraglutide, most likely due to once-weekly versus once-daily injections, respectively. Further research is needed to compare head-to-head CV outcomes among other GLP-1 receptor agonists.
Are gila monsters protected by the government?
Conservation status. Gila monsters are listed as Near Threatened by the IUCN. In 1952, the Gila monster became the first venomous animal to be given legal protection. Now Gila monsters are protected in all states of their distribution.
What are the characteristics of a Gila monster?
Head with bead-like scales and strong forelegs and claws suitable for digging. The Gila monster is found in the Southwestern United States and Mexico, a range including Sonora, Arizona, parts of California, Nevada, Utah, and New Mexico (potentially including Baja California).
Is there a Gila monster in Baja California?
The Gila monster is found in the Southwestern United States and Mexico, a range including Sonora, Arizona, parts of California, Nevada, Utah, and New Mexico. No records have been given from Baja California.
What time of day are gila monsters most active?
Gila monsters spend 90% of their time underground in burrows or rocky shelters. They are active in the morning during the dry season (spring and early summer); later in the summer, they may be active on warm nights or after a thunderstorm. They maintain a surface body temperature of about 30 °C (86 °F).