What is inositol made of?
(NCI04) Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate.
What are the side effects of inositol in adults?
Possible Side Effects. Inositol is generally considered safe in adults. Side effects, if any, tend to be mild and may include nausea, stomach pain, tiredness, headache, and dizziness. Most side effects occur with doses greater than 12 g per day.
What are the side effects of inositol while breastfeeding?
However, mild side effects have been reported with doses of 12 grams per day or higher. These include nausea, gas, difficulty sleeping, headache, dizziness and tiredness ( 36 ). ). There are also not enough studies to determine the safety of the supplements while breastfeeding. However, breast milk seems to be naturally rich in inositol ( 39 ).
How does inositol work in the brain?
In the brain, inositol has been shown to produce an increase in serotonin receptor sensitivity. This activity produces an increase in GABA release. Some of the effects observed in the brain produced a relief in symptoms of anxiety and obsessive-compulsive disorders. In high doses, it has been shown to even reduce panic attacks.
What is myo myo-inositol?
Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural similarities to glucose and are involved in cellular signaling.
How does inositol work for PCOS?
Studies show that it works by normalizing hormonal levels. Women with Polycystic Ovary Syndrome (PCOS) have high levels of testosterone and free insulin. In addition to aiding with fertility, Inositol can lower testosterone and insulin. Normalizing hormones and insulin levels help reduce unwanted hair and weight gain.
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