What is squamous cell carcinoma with Basaloid features?
Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of oral squamous cell carcinoma with a predilection for the tongue and in other locations, such as floor of the mouth, palate, retromolar trigone, and gingival mucosa.
What causes Basaloid squamous cell carcinoma?
In basaloid squamous cell carcinoma, the DNA that controls these cells is damaged, leading to an overgrowth of cells that forms a tumor. The exact cause of why this happens in some people and not others is unknown, but factors like smoking and drinking alcohol may be related to the cause of this cancer.
What is a Basaloid cell?
Basaloid cells are a feature of adenoid cystic carcinoma, but many cells have clear cytoplasm and irregular, angular, hyperchromatic nuclei. A characteristic cribriform pattern is rare and minimal in basal cell adenoma, and infiltration and perineural invasion are definitely not features of basal cell adenoma.
What is a Basaloid Tumour?
Basaloid tumours are defined as those that appear more blue than pink on haematoxylin and eosin (H&E) staining. Basophilia is a consequence of a high nuclear:cytoplasmic ratio and relatively con- densed nuclear chromatin. Basal cell carcinoma (BCC) is the prototypical basaloid skin tumour.
What is a Basaloid neoplasm?
Basaloid tumors of the salivary glands are a heterogeneous group of benign and malignant lesions characterized by small tumor cells with round or ovoid nuclei surrounded by a thin rim of cytoplasm.
What is Basaloid carcinoma?
Abstract. Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of cancer that mainly arises in the upper aerodigestive tract. This study reviews the clinico-pathological features and follow-up of a series of cases occurring in the head and neck.
What is Basaloid tumor?
Where do most Verrucous carcinoma develop?
Verrucous carcinoma may occur in various head and neck locations, as well as in the genitalia or sole of the foot. The oral cavity is the most common site of this tumor.