What is telaprivir (telaprevir)?
Telaprevir is an orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex.
What is Telaprevir (VX-950)?
Telaprevir ( VX-950 ), marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C co-developed by Vertex Pharmaceuticals and Johnson & Johnson. It is a member of a class of antiviral drugs known as protease inhibitors. Specifically, telaprevir inhibits…
Does telaprevir cause hepatic decompensation in cirrhosis?
In addition, when combined with peginterferon and ribavirin, telaprevir has been associated with cases of hepatic decompensation in patients with preexisting cirrhosis. Telaprevir is an orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV).
Is ribavirin more effective than telaprevir in genotype 1?
The standard therapy of pegylated interferon and ribavirin is less effective than telaprevir in those with genotype 1.
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