Where does clear cell endometrial cancer spread?
The tumor is aggressive and spreads quickly into the myometrium and the lymphatic system. Thus even in presumed early stages, lymphadenectomy and omentectomy should be included in the surgical approach.
How aggressive is clear cell carcinoma?
Clear cell carcinoma (CCC) comprises a rare yet an aggressive subtype, accounting for less than 5% of all uterine carcinomas. Several clinicopathologic features have been predictive of poor prognosis; however, data remain controversial.
How is clear cell carcinoma treated?
Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy , chemotherapy , biological therapy , or targeted therapy.
Can clear cell carcinoma be cured?
RCC can often be cured if it is diagnosed and treated surgically while still confined to the kidney and the immediately surrounding tissue. The probability of a cure is commensurate with the degree or stage of tumor dissemination.
Is clear cell carcinoma fatal?
The 5-year survival rate for patients with ccRCC is 50-69%. When ccRCC is already large or has spread to other parts of the body, treatment is more difficult and the 5-year survival rate is about 10%.
Does clear cell cancer come back?
Conclusion: Ovarian clear cell carcinoma predominantly recurs in multiple sites and it is associated with a high mortality rate and short post-recurrence survival. When recurrences are limited to a single site, or only to lymph nodes, the median post-recurrence survival is longer.
How fast does clear cell carcinoma grow?
Clear cell carcinoma (0.86 cm/year) tended to grow faster than papillary cell carcinoma (0.28 cm/year) (P = 0.066).
Can endometrial cancer come back?
Endometrial cancer is most likely to come back within the first few years after treatment, so an important part of your treatment plan is a specific schedule of follow-up visits after treatment ends.