How do you administer ganciclovir IV?
The drug should be given as a constant intravenous injection over a minimum of 1 hour. Each dose of ganciclovir is put in 100 or 250 mL bags. The I.V. solution should be warmed up to room temperature before administration.
How do you give ganciclovir?
Dosing
- Adults and teenagers—Dose is based on body weight and must be determined by your doctor. At first, 5 mg per kilogram (2.3 mg per pound) of body weight is injected into a vein every twelve hours for fourteen to twenty-one days.
- Children—Use and dose must be determined by your doctor.
Does ganciclovir need a filter?
Several responses from UHC members specified ganciclovir as a medication that requires filtration.
How long does ganciclovir take to work?
This usually happens within 1 to 2 weeks of starting treatment.
What is cytovene used for?
It is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received organ or bone marrow transplants. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness.
Which type of contact and excretion precautions should be taken when handling ganciclovir?
1. Avoid direct contact of skin or mucous membranes with diluted solution 2. Wear gloves for administering drug and contact with urine contaminated items 3.
How do you monitor ganciclovir?
When ganciclovir is administered on an outpatient basis for the treatment of CMV retinitis, follow-up with a CBC count once per week (monitoring for hematological toxicity) is necessary. Monitoring electrolytes at the same time is prudent.
What is the cost of cytovene?
The cost for Cytovene intravenous powder for injection 500 mg is around $134 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Cytovene is available, see ganciclovir prices.
Is ganciclovir a chemo drug?
Conclusions: Ganciclovir is the only antiviral chemotherapy which reduces the risk of CMV infection or disease after most types of major transplantation.
What is CMV retinitis?
Cytomegalovirus (CMV) Retinitis is a virus that may infect the retina and potentially cause irreversible vision loss due to retinal detachment or destruction.
What class drug is ganciclovir?
Ganciclovir is in a class of medications called antivirals. It works by preventing the spread of CMV disease or slowing the growth of CMV.
Is ganciclovir an immunosuppressant?
Ganciclovir is an antiviral medication used to prevent or treat infections caused by Cytomegalovirus (CMV). Liver transplant recipients are susceptible to CMV due to immunosuppressant drugs. Ganciclovir will not cure CMV eye infection, but it may help prevent the symptoms from becoming worse.
What is the initial dosage of Cytovene IV?
Induction Dosage: The recommended initial dosage of Cytovene-IV for patients with normal renal function is 5 mg/kg (given intravenously at a constant rate over 1 hour) every 12 hours for 14 to 21 days.
How often should I take Cytovene IV for retinitis?
Recommended Dosage for Treatment of CMV Retinitis in Adult Patients with Normal Renal Function. Maintenance Dosage: Following induction treatment, the recommended maintenance dosage of CYTOVENE-IV is 5 mg/kg (given intravenously at a constant rate over 1 hour) once daily for 7 days per week, or 6 mg/kg once daily for 5 days per week.
How do you reconstitute lyophilized Cytovene IV?
1. Reconstitution Instructions: a) Reconstitute lyophilized Cytovene-IV by injecting 10 mL of sterile water for injection, USP, into the vial. Do not use bacteriostatic water for injection containing parabens. It is incompatible with Cytovene-IV and may cause precipitation.
How does Cytovene-iv affect fertility?
Impairment of Fertility: Based on animal data and limited human data, Cytovene-IV may cause temporary or permanent inhibition of spermatogenesis in males and suppression of fertility in females [see Warnings and Precautions (5.3)].